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Article

A susceptibility locus for papillary thyroid carcinoma on chromosome 8q24.

Cancer research - 15 Jan 2009

He Huiling, Nagy Rebecca, Liyanarachchi Sandya, Jiao Hong, Li Wei, Suster Saul, Kere Juha, de la Chapelle Albert

Abstract excerpt

Papillary thyroid carcinoma (PTC) displays higher heritability than most other cancers. To search for genes predisposing to PTC, we performed a genome-wide linkage analysis in a large family with PTC and melanoma. Among several peaks the highest was at 8q24, with a maximum nonparametric linkage (NPL) score of 7.03. Linkage analysis was then broadened to comprise 25 additional PTC families that produced a maximum...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19147577
DOI: 10.1158/0008-5472.CAN-08-1071
PMCID: PMC2634601

Genes

SLA
NPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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