Article
Uncoupling protein 2 polymorphisms as risk factors for NTDs.
Birth defects research. Part A, Clinical and molecular teratology - 1 Feb 2009
Mitchell Adam, Pangilinan Faith, Van der Meer Julie, Molloy Anne M, Troendle James, Conley Mary, Kirke Peadar N, Scott John M, Brody Lawrence C, Mills James L
Abstract excerpt
BACKGROUND: Both environmental and genetic factors are involved in the etiology of NTDs. Inadequate folate intake and obesity are important environmental risk factors. Several folate-related genetic variants have been identified as risk factors; however, little is known about how genetic variants relate to the increased risk seen in obese women. Uncoupling Protein 2 (UCP2) is an attractive candidate to screen for...
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