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Article

Glomerular Transcriptome Changes Associated with Lipopolysaccharide-Induced Proteinuria

1 Jan 2009

Abstract excerpt

BACKGROUND: Global gene expression patterns have recently been characterized in normal glomeruli, but gene expression changes that accompany glomerular disease remain poorly characterized. METHOD: Here, we mapped global glomerular gene expression profile changes occurring in conjunction with lipopolysaccharide (LPS)-induced proteinuria in mice. RESULTS: We observed dramatic transcriptional reprogramming in...

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PMID: 19136817
DOI: 10.1159/000191469

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