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Whole-transcriptome analysis of UUO mouse model of renal fibrosis reveals new molecular players in kidney diseases

18 May 2016

Abstract excerpt

Transcriptome analysis by RNA-seq technology allows novel insights into gene expression and regulatory networks in health and disease. To better understand the molecular basis of renal fibrosis, we performed RNA-seq analysis in the Unilateral Ureteric Obstruction (UUO) mouse model. We analysed sham operated, 2- and 8-day post-ligation renal tissues. Thousands of genes with statistical significant changes in their...

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PMID: 27189340
DOI: 10.1038/srep26235

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