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Article

Increased susceptibility to exacerbated liver injury in hypercholesterolemic ApoE-deficient mice: potential involvement of oxysterols.

American journal of physiology. Gastrointestinal and liver physiology - 1 Mar 2009

Ferré Natàlia, Martínez-Clemente Marcos, López-Parra Marta, González-Périz Ana, Horrillo Raquel, Planagumà Anna, Camps Jordi, Joven Jorge, Tres Alba, Guardiola Francesc, Bataller Ramón, Arroyo Vicente, Clària Joan

Abstract excerpt

The contribution of metabolic factors to the severity of liver disease is not completely understood. In this study, apolipoprotein E-deficient (ApoE-/-) mice were evaluated to define potential effects of hypercholesterolemia on the severity of carbon tetrachloride (CCl4)-induced liver injury. Und...

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Identifiers

PMID: 19136384
DOI: 10.1152/ajpgi.00547.2007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19136384-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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