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Article

Di-(2-ethylhexyl) phthalate accelerates atherosclerosis in apolipoprotein E-deficient mice.

Archives of toxicology - 1 Jan 2016

Zhao Jin-Feng, Hsiao Sheng-Huang, Hsu Ming-Hua, Pao Kuan-Chuan, Kou Yu Ru, Shyue Song-Kun, Lee Tzong-Shyuan

Abstract excerpt

Di-(2-ethylhexyl) phthalate (DEHP) is associated with atherosclerosis-related cardiovascular disease complications, but we lack direct evidence of its unfavorable effect on atherogenesis. In this study, we aimed to clarify in vivo and in vitro the contribution of DEHP to the development of atherosclerosis and its underlying mechanisms. Apolipoprotein E-deficient (apoE(-/-)) mice chronically treated with DEHP for...

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PMID: 25270622
DOI: 10.1007/s00204-014-1377-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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