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Article

Oxysterols in biological systems: sources, metabolism and pathophysiological relevance

1 Dec 2006

Abstract excerpt

Oxysterols are the 27-carbon products of cholesterol oxidation by both enzymic and non-enzymic mechanisms. Their roles in cholesterol homeostasis, as well as in diseases in which oxidative damage and lipid peroxidation are implicated (e.g. atherosclerosis), have been investigated extensively. However, there are a number of important considerations regarding the physiological/pathophysiological functions and...

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PMID: 17207307
DOI: 10.1179/135100006x155003

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