Article
No association between the C-1562T polymorphism in the promoter of matrix metalloproteinase-9 gene and non-small cell lung carcinoma.
Lung cancer (Amsterdam, Netherlands) - 1 Aug 2005
Wang Yimin, Fang Shumei, Wei Lizhen, Wang Rui, Jin Xia, Wen Denggui, Li Yan, Guo Wei, Wang Na, Zhang Jianhui
Abstract excerpt
The matrix metalloproteinases (MMPs) are a family of highly conserved metal-dependent proteolytic enzymes, their main function is to degrade different components of extracellular matrix (ECM). Moreover, they play roles in regulation of cell growth, apoptosis, angiogenesis and immune surveillance. Natural sequence variations in the MMP genes may result in differential expression of MMPs in different individuals...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
