Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of association between aspirin responsiveness and seven candidate gene haplotypes in patients with symptomatic vascular disease.

Thrombosis and haemostasis - 1 Jan 2009

Kunicki Thomas J, Williams Shirley A, Nugent Diane J, Harrison Paul, Segal Helen C, Syed Anila, Rothwell Peter M

Abstract excerpt

We studied the effect of prophylactic aspirin (ASA) ingestion on platelet function in 463 patients with stroke, transient ischemic attack (TIA) or acute coronary disease (ACD), using the Platelet Function Analyzer-100 (PFA-100). We correlated ASA responsiveness with haplotypes of seven candidate genes, selected for their documented role in platelet function, namely, the genes for integrins alpha2beta1and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclooxygenase 1
Share to Epinephrine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Integrin alpha2

Share to Integrin beta3

Share to Platelet Function Tests

Share to Platelet Glycoprotein GPIb-IX Complex

Share to Platelet Membrane Glycoproteins

Share to Receptors, Purinergic P2

Source

Identifiers

PMID: 19132198

Genes

ACD
ITGA2
ITGB3
PTGS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of association between aspirin responsiveness and seven candidate gene haplotypes in patients with symptomatic vascular disease.PMID 19132198Read ↗

Platelet function and antiplatelet therapy in cardiovascular disease: implications of genetic polymorphisms.Semantic proximity Read ↗

Stroke and aspirin non-responder patients: relation with hypertension and platelet response to adenosine diphosphate.Semantic proximity Read ↗

Lack of association between gene sequence variations of platelet membrane receptors and aspirin responsiveness detected by the PFA-100 system in patients with coronary artery disease.Semantic proximity Read ↗

Lack of association between the 807 C/T polymorphism of glycoprotein Ia gene and post-treatment platelet reactivity after aspirin and clopidogrel in patients with acute coronary syndrome.Semantic proximity Read ↗

Polymorphisms associated with in vitro aspirin resistance are not associated with clinical outcomes in patients with coronary artery disease who report regular aspirin use.Semantic proximity Read ↗

Epoxidase inhibitor-aspirin resistance and the relationship with genetic polymorphisms: a reviewSemantic proximity Read ↗

Association of platelet ADP receptor variant rs1371097 with inadequate platelet response to aspirin in Indian patients.Semantic proximity Read ↗

Platelet ADP receptor (P2RY1) polymorphism and the risk of inadequate platelet response to aspirin: Study in patients with ischemic strokeSemantic proximity Read ↗

Glycoprotein IIIA gene (PlA) polymorphism and aspirin resistance: is there any correlation?Semantic proximity Read ↗

The Impact of Single Nucleotide Polymorphisms and Other Mechanisms on Aspirin Resistance.Semantic proximity Read ↗

Genetic Association Study and Machine Learning to Investigate Differences in Platelet Reactivity in Patients with Acute Ischemic Stroke Treated with AspirinSemantic proximity Read ↗

Frequency of Genetic Polymorphisms of COX1 , GPIIIa and P2Y1 in a Chinese Population and Association with Attenuated Response to AspirinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.