Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Impact of Single Nucleotide Polymorphisms and Other Mechanisms on Aspirin Resistance.

Cardiovascular & hematological disorders drug targets - 1 Jan 2025

Nuzhdina Natalia Sergeevna, Kurguzov Aleksei Vitalievich, Sergeevichev David Sergeevich

Abstract excerpt

Atherosclerosis and ischemic events play a pivotal role in the pathogenesis of several cardiovascular diseases (CVD). The primary aim of preventing recurrent thrombosis in patients who underwent cardiovascular surgery is the antiplatelet agent administration. Nevertheless, despite the aspirin therapy or double (aspirin plus clopidogrel) therapy, the effectiveness of antithrombotic treatment remains controversial....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspirin
Share to Cardiovascular Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance

Share to AR gene

Share to HPR gene

Share to Platelet Aggregation Inhibitors

Share to Polymorphism, Single Nucleotide

Share to Thrombosis

Source

Identifiers

PMID: 40192046
DOI: 10.2174/011871529X361464250319084053

Genes

AR
HPR
PEAR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Impact of Single Nucleotide Polymorphisms and Other Mechanisms on Aspirin Resistance.PMID 40192046Read ↗

A brief review on the mechanisms of aspirin resistance.Semantic proximity Read ↗

Epoxidase inhibitor-aspirin resistance and the relationship with genetic polymorphisms: a reviewSemantic proximity Read ↗

Pharmacogenetics of the antiplatelet effect of aspirin.Semantic proximity Read ↗

Model based on single-nucleotide polymorphism to discriminate aspirin resistance patients.Semantic proximity Read ↗

Frequency of Genetic Polymorphisms of COX1 , GPIIIa and P2Y1 in a Chinese Population and Association with Attenuated Response to AspirinSemantic proximity Read ↗

The emergent phenomenon of aspirin resistance: insights from genetic association studies.Semantic proximity Read ↗

A study into the genetic basis of aspirin resistance in Pakistani patients with coronary artery disease.Semantic proximity Read ↗

The associations of candidate gene polymorphisms with aspirin resistance in patients with ischemic disease: a meta-analysis.Semantic proximity Read ↗

Influence of genetic polymorphisms on platelet function, response to antiplatelet drugs and clinical outcomes in patients with coronary artery disease.Semantic proximity Read ↗

Role of platelet glycoprotein polymorphisms in cardiovascular diseases.Semantic proximity Read ↗

Effects of four novel genetic polymorphisms on clopidogrel efficacy in Chinese acute coronary syndromes patients.Semantic proximity Read ↗

Platelet function and antiplatelet therapy in cardiovascular disease: implications of genetic polymorphisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.