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Article

Frequency of Genetic Polymorphisms of COX1 , GPIIIa and P2Y1 in a Chinese Population and Association with Attenuated Response to Aspirin

1 Jun 2007

Abstract excerpt

BACKGROUND: Aspirin is a frequently prescribed drug for primary and secondary prevention of myocardial infarction, stroke and cardiovascular death. However, aspirin resistance may affect up to 45% of the population. Little is known on the role of genetic factors that contribute to resistance or augmented response to aspirin in different human populations. METHODS: In a large sample of nonsmoker, medication-free...

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PMID: 17559347
DOI: 10.2217/14622416.8.6.577

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