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Article

Sgt1, a co-chaperone of Hsp90 stabilizes Polo and is required for centrosome organization.

The EMBO journal - 4 Feb 2009

Martins Torcato, Maia André F, Steffensen Soren, Sunkel Claudio E

Abstract excerpt

Sgt1 was described previously in yeast and humans to be a Hsp90 co-chaperone and required for kinetochore assembly. We have identified a mutant allele of Sgt1 in Drosophila and characterized its function. Mutations in sgt1 do not affect overall kinetochore assembly or spindle assembly checkpoint. sgt1 mutant cells enter less frequently into mitosis and arrest in a prometaphase-like state. Mutations in sgt1...

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Identifiers

PMID: 19131964
DOI: 10.1038/emboj.2008.283
PMCID: PMC2637337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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