Article
Association of (pro)renin receptor gene polymorphism with blood pressure in Japanese men: the Ohasama study.
American journal of hypertension - 1 Mar 2009
Hirose Takuo, Hashimoto Masahiro, Totsune Kazuhito, Metoki Hirohito, Asayama Kei, Kikuya Masahiro, Sugimoto Ken, Katsuya Tomohiro, Ohkubo Takayoshi, Hashimoto Junichiro, Rakugi Hiromi, Takahashi Kazuhiro, Imai Yutaka
Abstract excerpt
BACKGROUND: Recent studies have revealed that (pro)renin receptor ((P)RR), a newly identified member of the renin-angiotensin system (RAS), is associated with blood pressure regulation in animals. However, there is no information on (P)RR in humans. We investigated the association of (P)RR gene polymorphisms with blood pressure in a Japanese population. METHODS: Subjects (n = 1,112) were recruited from...
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