Article
Association between angiotensin II type 1 receptor gene polymorphism and essential hypertension: the Ohasama Study.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Aug 2004
Sugimoto Ken, Katsuya Tomohiro, Ohkubo Takayoshi, Hozawa Atsushi, Yamamoto Koichi, Matsuo Akiko, Rakugi Hiromi, Tsuji Ichiro, Imai Yutaka, Ogihara Toshio
Abstract excerpt
Gene targeting approaches have suggested that the angiotensin II type 1 receptor (AT1R) is involved in blood pressure (BP) regulation and modulation of the effect of angiotensin II. The A1166C polymorphism of the AT1 receptor gene (AT1R/A1166C) is associated with hypertension in Caucasians, but not in Japanese. The goal of this study, the Ohasama Study, was to examine the association between AT1R/A1166C and...
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