Article
Comprehensive analysis of the renin-angiotensin gene polymorphisms with relation to hypertension in the Japanese.
Journal of hypertension - 1 Aug 2000
Kato N, Sugiyama T, Morita H, Kurihara H, Furukawa T, Isshiki T, Sato T, Yamori Y, Yazaki Y
Abstract excerpt
BACKGROUND: Components of the renin-angiotensin (R-A) system have been repeatedly investigated as candidate genes for essential hypertension. In particular, suggestive or significant association has been detected in some studies for the angiotensinogen M235T, angiotensin I-converting enzyme I/D, angiotensin II type 1 receptor A1166C, and aldosterone synthase C-344T polymorphisms, although the results remain...
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