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Article

alpha-Adducin Gly460Trp polymorphism is associated with low renin hypertension in younger subjects in the Ohasama study.

Journal of hypertension - 1 Sept 2002

Sugimoto Ken, Hozawa Atsushi, Katsuya Tomohiro, Matsubara Mitsunobu, Ohkubo Takayoshi, Tsuji Ichiro, Motone Masaharu, Higaki Jitsuo, Hisamachi Shigeru, Imai Yutaka, Ogihara Toshio

Abstract excerpt

BACKGROUND: The Gly460Trp polymorphism of the alpha-adducin gene (ADD-1 ) has been examined as a candidate gene for essential hypertension with salt sensitivity in the Caucasian population. However, we failed to detect a positive association between the Gly460Trp polymorphism of ADD-1 and hypertension in a small series of Japanese subjects. OBJECTIVE: To examine the precise association between the Gly460Trp...

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PMID: 12195119
DOI: 10.1097/00004872-200209000-00022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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