Article
Association Between Polymorphisms of ADRBK1 Gene and Plasma Renin Activity in Hypertensive Patients: A Case-Control Study.
Medical science monitor : international medical journal of experimental and clinical research - 24 Aug 2016
Li Yu, Li Nanfang, Yao Xiaoguang, Heizati Mulalibieke, Zhang Delian, Zhu Qing, Chang Guijuan, Zhang Xiangyang
Abstract excerpt
BACKGROUND Renin is the first step of the RAS cascade, which is a major regulator of salt-volume homeostasis. Adrenergic beta receptor kinase 1 (ADRBK1) plays important roles in regulating blood pressure via the epithelial Na+ channel (ENaC), which plays an important role in Na+ reabsorption in the renal collecting duct. The present case-control study was designed to investigate the potential relationship between...
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