Article
Identification of polymorphisms in the Toll-like receptor gene and the association with allergic rhinitis.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Mar 2010
Kang Inhong, Oh Yeon-Kyun, Lee Sang Heon, Jung Ha Min, Chae Soo-Cheon, Lee Jae Hoon
Abstract excerpt
The TLRs gene encodes the principal innate immunity receptor in humans. The TLR2 Arg753Gln and Arg677Trp polymorphisms have been associated with a reduced response of monocytes and cell lines to challenge with mycobacteria. The TLR4 Asp299Gly and Thr399Ile polymorphisms have been associated with...
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