Article
Accuracy of the BRCAPRO model among women with bilateral breast cancer.
Cancer - 15 Feb 2009
Ready Kaylene J, Vogel Kristen J, Atchley Deann P, Broglio Kristine R, Solomon Kimberly K, Amos Christopher, Lu Karen H, Hortobagyi Gabriel N, Arun Banu
Abstract excerpt
BACKGROUND: The likelihood of identifying a BRCA mutation was often calculated using the BRCAPRO model. A previous study suggested that this model may overestimate the chance of detecting a BRCA mutation among women diagnosed with bilateral breast cancer. Studies also suggested that few patients with bilateral breast cancer whose age at first diagnosis is >40 years were mutation carriers. The objectives of this...
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