Article
BRCA1 and BRCA2 mutations as prognostic factors in bilateral breast cancer patients.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Sept 2004
Rogozińska-Szczepka J, Utracka-Hutka B, Grzybowska E, Maka B, Nowicka E, Smok-Ragankiewicz A, Zientek H, Steffen J, Wojciechowska-Łacka A
Abstract excerpt
BACKGROUND: Incidence of primary bilateral breast cancer (BC) is rare and does not exceed 5%. BRCA1/2 mutation carriers diagnosed with breast cancer have a strong life time risk of developing contralateral breast cancer (53% versus 2%). PATIENTS AND METHODS: A group of 108 patients with bilateral breast cancer, who reported at our Cancer Centres from 2000 to 2002, were subjected to genetic testing. Similarities...
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