Article
Sulfotransferase 1A1 haplotypes associated with oral squamous cell carcinoma susceptibility in male Taiwanese.
Carcinogenesis - 1 Feb 2009
Chung Yu-Ting, Hsieh Ling-Ling, Chen I-How, Liao Chun-Ta, Liou Saou-Hsing, Chi Chin-Wen, Ueng Yune-Fang, Liu Tsung-Yun
Abstract excerpt
We have previously demonstrated that betel quid containing safrole induced DNA adducts are highly associated with the development of oral squamous cell carcinoma (OSCC) in Taiwan. Sulfotransferase (SULT) is essential for the formation of these adducts. To elucidate the effects of SULT1A1 haplotypes on OSCC susceptibility, 160 male OSCC cases and 218 age- and sex-matched controls were screened for...
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