Article
Sulfotransferase 1A1 polymorphism and gastric cancer risk: a pilot case-control study.
Cancer letters - 18 Nov 2005
Boccia Stefania, Persiani Roberto, La Torre Giuseppe, Rausei Stefano, Arzani Dario, Gianfagna Francesco, Romano-Spica Vincenzo, D'Ugo Domenico, Ricciardi Gualtiero
Abstract excerpt
Sulfotransferases (SULT) catalyse both the bioactivation and detoxification of a wide range of promutagens and carcinogens. The SULT1A1 gene possesses a G-->A polymorphism that results in a Arg to His substitution at codon 213, and the His allele has been shown to have a low activity and thermal stability. To test the hypothesis that individuals carrying the variant allele may be at high risk of gastric cancer,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.