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Article

Association of a functional variant of the nitric oxide synthase 1 gene with personality, anxiety, and depressiveness.

Development and psychopathology - 1 Nov 2012

Kurrikoff Triin, Lesch Klaus-Peter, Kiive Evelyn, Konstabel Kenn, Herterich Sabine, Veidebaum Toomas, Reif Andreas, Harro Jaanus

Abstract excerpt

A functional promoter polymorphism of the nitric oxide synthase 1 gene first exon 1f variable number tandem repeat (NOS1 ex1f-VNTR) is associated with impulsivity and related psychopathology. Facets of impulsivity are strongly associated with personality traits; maladaptive impulsivity with neuroticism; and adaptive impulsivity with extraversion. Both high neuroticism and low extraversion predict anxiety and...

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Source

Identifiers

PMID: 23062293
DOI: 10.1017/S0954579412000661

Genes

NOS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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