Article
Risk conferred by HLA-DR and DQ for type 1 diabetes in 0-35-year age group in Sweden.
Annals of the New York Academy of Sciences - 1 Dec 2008
Sanjeevi Carani B, Sedimbi Saikiran K, Landin-Olsson Mona, Kockum Ingrid, Lernmark Ake
Abstract excerpt
UNLABELLED: HLA DR4-DQ8 and DR3-DQ2 haplotypes account for 89% of newly diagnosed cases of type 1 diabetes (T1D) in Sweden. The presence of a single copy of DQ6 confers protection. The aim of the present study is to evaluate whether the risk conferred by high risk HLA DR and DQ to T1D is similar in all regions of Sweden and see whether there are any significant regional differences. The subjects comprised 799...
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