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Article

Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis.

PLoS genetics - 1 Jan 2009

Shah Svati H, Freedman Neil J, Zhang Lisheng, Crosslin David R, Stone David H, Haynes Carol, Johnson Jessica, Nelson Sarah, Wang Liyong, Connelly Jessica J, Muehlbauer Michael, Ginsburg Geoffrey S, Crossman David C, Jones Christopher J H, Vance Jeffery, Sketch Michael H, Granger Christopher B, Newgard Christopher B, Gregory Simon G, Goldschmidt-Clermont Pascal J, Kraus William E, Hauser Elizabeth R

Abstract excerpt

Neuropeptide Y (NPY) is a strong candidate gene for coronary artery disease (CAD). We have previously identified genetic linkage to familial CAD in the genomic region of NPY. We performed follow-up genetic, biostatistical, and functional analysis of NPY in early-onset CAD. In familial CAD (GENECA...

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Identifiers

PMID: 19119412
DOI: 10.1371/journal.pgen.1000318
PMCID: PMC2602734

Genes

NPY
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19119412-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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