Article
Questioning the ubiquity of neofunctionalization.
PLoS computational biology - 1 Jan 2009
Gibson Todd A, Goldberg Debra S
Abstract excerpt
Gene duplication provides much of the raw material from which functional diversity evolves. Two evolutionary mechanisms have been proposed that generate functional diversity: neofunctionalization, the de novo acquisition of function by one duplicate, and subfunctionalization, the partitioning of ancestral functions between gene duplicates. With protein interactions as a surrogate for protein functions, evidence...
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