Evolution of specific protein-protein interaction sites following gene duplication.

Abstract excerpt

Gene duplication is a common evolutionary process that leads to the expansion and functional diversification of protein subfamilies. The evolutionary events that cause paralogous proteins to bind different protein ligands (functionally diverged interfaces) are investigated and compared to paralogous proteins that bind the same protein ligand (functionally preserved interfaces). We find that functionally diverged...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Binding Sites
• Share to Gene Duplication
• Share to Hydrogen Bonding