Article
Relationship between gene duplicability and diversifiability in the topology of biochemical networks.
BMC genomics - 8 Jul 2014
Guo Zhanyong, Jiang Wen, Lages Nuno, Borcherds Wade, Wang Degeng
Abstract excerpt
BACKGROUND: Selective gene duplicability, the extensive expansion of a small number of gene families, is universal. Quantitatively, the number of genes (P(K)) with K duplicates in a genome decreases precipitously as K increases, and often follows a power law (P(k)∝k-α). Functional diversification, either neo- or sub-functionalization, is a major evolution route for duplicate genes. RESULTS: Using three lines of...
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