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Article

Oxidative stress and disruption of labile iron generate specific auxotrophic requirements in Salmonella enterica.

Microbiology (Reading, England) - 1 Jan 2009

Thorgersen Michael P, Downs Diana M

Abstract excerpt

The response of a cell to integrated stresses was investigated using environmental and/or genetic perturbations that disrupted labile iron homeostasis and increased oxidative stress. The effects of the perturbations were monitored as nutritional requirements, and were traced to specific enzymic targets. A yggX gshA cyaY mutant strain required exogenous thiamine and methionine for growth. The thiamine requirement,...

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Identifiers

PMID: 19118370
DOI: 10.1099/mic.0.020727-0
PMCID: PMC6756756

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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