Article
Cobalt targets multiple metabolic processes in Salmonella enterica.
Journal of bacteriology - 1 Nov 2007
Thorgersen Michael P, Downs Diana M
Abstract excerpt
Cobalt is essential for growth of Salmonella enterica and other organisms, yet this metal can be toxic when present in excess. Wild-type Salmonella exhibits several metabolic defects when grown in the presence of cobalt, some of which generate visible growth consequences. Work herein identifies sulfur assimilation, iron homeostasis, and Fe-S cluster metabolism as targets for cobalt toxicity. In each case it is...
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