Article
Phenotype and gene expression of human mesenchymal stem cells in alginate scaffolds.
Tissue engineering. Part A - 1 Jul 2009
Duggal Shivali, Frønsdal Katrine B, Szöke Krisztina, Shahdadfar Aboulghassem, Melvik Jan Egil, Brinchmann Jan E
Abstract excerpt
Human mesenchymal stem cells (MSC) are popular candidates for tissue engineering. MSC are defined by their properties in two-dimensional (2D) culture systems. Cells in 2D are known to differ from their in vivo counterparts in cell shape, proliferation, and gene expression. Little is so far known about the phenotype and gene expression of cells in three-dimensional (3D) culture systems. To begin to unravel the...
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