Article
Assessment of the Behavior of Mesenchymal Stem Cells Immobilized in Biomimetic Alginate Microcapsules.
Molecular pharmaceutics - 2 Nov 2015
Garate Ane, Ciriza Jesús, Casado Javier G, Blazquez Rebeca, Pedraz José Luis, Orive Gorka, Hernandez Rosa Maria
Abstract excerpt
The combination of mesenchymal stem cells (MSCs) and biomimetic matrices for cell-based therapies has led to enormous advances, including the field of cell microencapsulation technology. In the present work, we have evaluated the potential of genetically modified MSCs from mice bone marrow, D1-MSCs, immobilized in alginate microcapsules with different RGD (Arg-Gly-Asp) densities. Results demonstrated that the...
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