Independent rearrangement of Ig lambda genes in tissue culture-derived murine B cell lines.

doi:10.1093/intimm/3.7.711

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Article

Independent rearrangement of Ig lambda genes in tissue culture-derived murine B cell lines.

International immunology - 1 Jul 1991

Felsher D W, Ando D T, Braun J

Abstract excerpt

Rearrangement of the lambda light chain locus is considered a late event in pre-B cell differentiation which occurs after successful heavy chain and unsuccessful kappa light chain rearrangement. However, this view has recently been challenged by the observation of apparently independent lambda re...

Topics

Animals
Antigens, Differentiation, B-Lymphocyte
B-Lymphocytes
Cell Differentiation
Cell Line
Culture Techniques
Gene Rearrangement, B-Lymphocyte, Light Chain
Immunoglobulin Isotypes
Mice
Phenotype

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