Article
Simultaneously arising Ly-1(CD5) B cell lymphomas have identical expressed IgH and kappa-genes but different nonproductive heavy chain rearrangements.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 1990
Van Houten N, Haughton G
Abstract excerpt
A group of CD5(Ly-1) B cell lymphomas are described. They were derived from mice which received a common pool of syngeneic mouse spleen cells. Southern blot analysis revealed that the lymphomas exhibited an unusual set of Ig gene rearrangements. Six lymphomas analyzed had either of two rearrangem...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antigens, Differentiation
- Antigens, Ly
- Base Sequence
- Blotting, Southern
- CD5 Antigens
- Clone Cells
- DNA
- Gene Expression Regulation
- Gene Rearrangement, B-Lymphocyte
- Immunoglobulin Heavy Chains
- Immunoglobulin kappa-Chains
- Lymphoma
- Mice
- Molecular Sequence Data
- Restriction Mapping