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Article

Association between the SDF1-3'A allele and high levels of CD34(+) progenitor cells mobilized into peripheral blood in humans.

British journal of haematology - 1 Apr 2001

Benboubker L, Watier H, Carion A, Georget M T, Desbois I, Colombat P, Bardos P, Binet C, Domenech J

Abstract excerpt

Some patients unexpectedly fail to mobilize sufficient numbers of haematopoietic progenitor cells (HPCs) into the peripheral blood for autologous transplantation. Considering the important role of the chemokine stromal cell-derived factor 1 (SDF-1) in HPC homing, we investigated a possible relationship between SDF1 gene polymorphism and HPC mobilization capacity in 63 patients with malignancy. Some 67% of the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11328308
DOI: 10.1046/j.1365-2141.2001.02717.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Association between the SDF1-3'A allele and high levels of CD34(+) progenitor cells mobilized into peripheral blood in humans.PMID 11328308Read ↗

Association of stromal cell-derived factor-1-3'A polymorphism to higher mobilization of hematopoietic stem cells CD34+ in Tunisian population.Semantic proximity Read ↗

The CXCL12-3'A allele is associated with a higher mobilization yield of CD34 progenitors to the peripheral blood of healthy donors for allogeneic transplantation.Semantic proximity Read ↗

Polymorphism of CD44 influences the efficacy of CD34(+) cells mobilization in patients with hematological malignancies.Semantic proximity Read ↗

Contribution of genetics to hematopoietic stem cell mobilization: a genome-wide association study of 564 healthy donors mobilized with granulocyte colony-stimulating factor.Semantic proximity Read ↗

Analysis of a large single institution cohort of related donors fails to detect a relation between SDF1/CXCR4 or VCAM/VLA4 genetic polymorphisms and the level of hematopoietic progenitor cell mobilization in response to G-CSF.Semantic proximity Read ↗

SDF1-3'A gene polymorphism is associated with chronic myeloproliferative disease and thrombotic events.Semantic proximity Read ↗

Genetic variant of the G-CSF receptor gene is associated with lower mobilization potential and slower recovery of granulocytes after transplantation of autologous peripheral blood progenitor cells.Semantic proximity Read ↗

SDF1 gene variation is associated with circulating SDF1alpha level and endothelial progenitor cell number: the Bruneck Study.Semantic proximity Read ↗

CD34+ progenitors from MDS patients are unresponsive to SDF-1, despite high levels of SDF-1 in bone marrow plasmaSemantic proximity Read ↗

Impact of constitutional polymorphisms in VCAM1 and CD44 on CD34+ cell collection yield after administration of granulocyte colony-stimulating factor to healthy donors.Semantic proximity Read ↗

Stromal cell-derived factor-1 chemokine gene variant in blood donors and chronic myelogenous leukemia patients.Semantic proximity Read ↗

Impact of CD44 gene single nucleotide polymorphism (rs 13347) in mobilization of autologous HSCT.Semantic proximity Read ↗

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