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Article

SDF-1/CXCL12 and CXCR4 gene variants, and elevated serum SDF-1 levels are associated with preeclampsia.

Hypertension in pregnancy - 1 May 2017

Karakus Savas, Bagci Binnur, Bagci Gokhan, Sancakdar Enver, Yildiz Caglar, Akkar Ozlem, Cetin Ali

Abstract excerpt

OBJECTIVE: We aimed to compare the frequencies of stromal cell-derived factor-1 (SDF-1) 3'A and CXCR4 single-nucleotide polymorphisms (SNPs) and serum SDF-1 levels in patients with preeclampsia (PE). METHODS: In total, 89 women with PE and 89 control women were included in the study. Genotyping was done by polymerase chain reaction-restriction fragment length polymorphism method. Enzyme-linked immunosorbent assay...

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Source

Identifiers

PMID: 28001450
DOI: 10.1080/10641955.2016.1250904

Genes

CXCR4
CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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