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Article

The skeletal phenotypes of TRalpha and TRbeta mutant mice.

Journal of molecular endocrinology - 1 Apr 2009

Bassett J H Duncan, Williams Graham R

Abstract excerpt

Analysis of mice harbouring deletions or mutations of T(3) receptor alpha (TRalpha) and beta (TRbeta) have clarified the complex relationship between central and peripheral thyroid status and emphasised the essential but contrasting roles of T(3) in skeletal development and adult bone. These studies indicate that TRalpha1 is the predominant TR expressed in bone and that T(3) exerts anabolic actions during growth...

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Source

Identifiers

PMID: 19114539
DOI: 10.1677/JME-08-0142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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