Article
Maternal supply of BDNF to mouse fetal brain through the placenta.
Neurochemistry international - 1 Feb 2009
Kodomari Ikuko, Wada Etsuko, Nakamura Shun, Wada Keiji
Abstract excerpt
Gastrointestinal peptides and hormones are known to penetrate through the utero-placental barrier and regulate fetal development. In the present study, we tested permeation of maternal brain-derived neurotrophic factor (BDNF) to fetuses, using BDNF-gene deficient mice and exogenous BDNF administration. At embryonic day 13.5 (E13.5)-14.5, BDNF protein concentrations in the fetal brain of BDNF homozygous null...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
