Article
The Physiology of BDNF and Its Relationship with ADHD.
Molecular neurobiology - 1 Dec 2015
Liu De-Yi, Shen Xue-Mei, Yuan Fang-Fen, Guo Ou-Yang, Zhong Yan, Chen Jian-Guo, Zhu Ling-Qiang, Wu Jing
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) is a major neurotrophin in the central nervous system that plays a critical role in the physiological brain functions via its two independent receptors: tropomyosin-related kinase B (TrkB) and p75, especially in the neurodevelopment. Disrupting of BDNF and its downstream signals has been found in many neuropsychological diseases, including attention-deficit hyperactivity...
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