Article
Novel function of C5 protein as a metabolic stabilizer of M1 RNA.
FEBS letters - 22 Jan 2009
Kim Yool, Lee Younghoon
Abstract excerpt
Escherichia coli RNase P is a ribonucleoprotein composed of a large RNA subunit (M1 RNA) and a small protein subunit (C5 protein). We examined if C5 protein plays a role in maintaining metabolic stability of M1 RNA. The sequestration of C5 protein available for M1 RNA binding reduced M1 RNA stability in vivo, and its reduced stability was recovered via overexpression of C5 protein. In addition, M1 RNA was rapidly...
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