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Article

Genotyping of celiac disease-related-risk haplotypes using a closed-tube polymerase chain reaction analysis of dried blood and saliva disk samples.

Analytical biochemistry - 1 Mar 2009

Ollikka Pia, Raussi Hanna-Mari, Laitala Ville, Jaakkola Lassi, Hovinen Jari, Hemmilä Ilkka, Ylikoski Alice

Abstract excerpt

Expansion of molecular diagnostics more widely into clinical routines requires simplified methods allowing automation. We developed a homogeneous, multilabel polymerase chain reaction (PCR) method based on time-resolved fluorometry, and studied the use of dried disk samples in PCR. Celiac disease-related HLA-DQA1*05, HLA-DQB1*02, and HLA-DQB1*0302 genotyping was used to verify the method with blood and saliva...

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Identifiers

PMID: 19111519
DOI: 10.1016/j.ab.2008.11.047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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