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Article

High-throughput genetic analysis using time-resolved fluorometry and closed-tube detection.

Analytical biochemistry - 15 Dec 2001

Nurmi J, Kiviniemi M, Kujanpää M, Sjöroos M, Ilonen J, Lövgren T

Abstract excerpt

Robust methods for genetic analysis are required for efficient exploitation of the constantly accumulating genetic information. We describe a closed-tube genotyping method suitable for high-throughput screening of genetic markers. The method is based on allele-specific probes labeled with an environment-sensitive lanthanide chelate, the fluorescence intensity of which is significantly increased upon PCR...

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Source

Identifiers

PMID: 11730345
DOI: 10.1006/abio.2001.5434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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