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Article

Differential regulation of aortic growth in male and female rodents is associated with AAA development.

The Journal of surgical research - 1 Aug 2009

Cho Brenda S, Woodrum Derek T, Roelofs Karen J, Stanley James C, Henke Peter K, Upchurch Gilbert R

Abstract excerpt

BACKGROUND: The objective was to examine effects of gonadal hormone manipulation on aortic diameter and macrophage infiltration in rodents during abdominal aortic aneurysm (AAA) formation. METHODS: Experiment 1: 17-beta estradiol and testosterone pellets were implanted in male (ME) and female (FT) rats. No pellet was implanted in shams (MES, FTS). Experiment 2: Testes and ovaries were removed from males (MO) and...

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Source

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Identifiers

PMID: 19111327
DOI: 10.1016/j.jss.2008.07.027
PMCID: PMC3205088

Genes

FOS
MOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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