Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects.

doi:10.1093/hmg/ddq078

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Article

Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects.

Human molecular genetics - 15 May 2010

Wang Kai, Baldassano Robert, Zhang Haitao, Qu Hui-Qi, Imielinski Marcin, Kugathasan Subra, Annese Vito, Dubinsky Marla, Rotter Jerome I, Russell Richard K, Bradfield Jonathan P, Sleiman Patrick M A, Glessner Joseph T, Walters Thomas, Hou Cuiping, Kim Cecilia, Frackelton Edward C, Garris Maria, Doran James, Romano Claudio, Catassi Carlo, Van Limbergen Johan, Guthery Stephen L, Denson Lee, Piccoli David, Silverberg Mark S, Stanley Charles A, Monos Dimitri, Wilson David C, Griffiths Anne, Grant Struan F A, Satsangi Jack, Polychronakos Constantin, Hakonarson Hakon

Abstract excerpt

Inflammatory bowel disease, including Crohn's disease (CD) and ulcerative colitis (UC), and type 1 diabetes (T1D) are autoimmune diseases that may share common susceptibility pathways. We examined known susceptibility loci for these diseases in a cohort of 1689 CD cases, 777 UC cases, 989 T1D cas...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20176734
DOI: 10.1093/hmg/ddq078
PMCID: PMC2860894

Genes

CCNY
HERC2
ICOSLG
PTPN22
TNFAIP3
TNFSF15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20176734-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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