Article
The past, present, and future of genetic associations in type 1 diabetes.
Current diabetes reports - 1 Oct 2011
Baker Peter R, Steck Andrea K
Abstract excerpt
Type 1 diabetes mellitus (T1DM) is an autoimmune disease affecting approximately one in 300 individuals in the United States. The majority of genetic research to date has focused on the heritability that predisposes to islet autoimmunity and T1DM. The evidence so far points to T1DM being a polygenic, common, complex disease with major susceptibility lying in the major histocompatibility complex (MHC) on...
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