Article
Association of two variants of the interferon-alpha receptor-1 gene with the presentation of hepatitis B virus infection.
European cytokine network - 1 Dec 2008
Song Le H, Xuan Nguyen T, Toan Nguyen L, Binh Vu Q, Boldt Angelica B, Kremsner Peter G, Kun Jürgen F J
Abstract excerpt
Interferon-alpha (IFNalpha) is a critical mediator of immunity to hepatitis B virus (HBV) infection. Although IFN has been used in the treatment of viral hepatitis for more than a decade, the role of IFN-alpha-receptor in HBV infection has not been intensively studied. We have evaluated the impact of two variants of the IFNAR1 gene on the outcome of HBV infection. Four hundred and fifty eight HBV-infected...
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