Article
Association of an intronic haplotype of the LIPC gene with hyperalphalipoproteinemia in two independent populations.
Journal of human genetics - 1 Jan 2008
Iijima Hiroshi, Emi Mitsuru, Wada Manabu, Daimon Makoto, Toriyama Sayumi, Koyano Satoru, Sato Hidenori, Hopkins Paul N, Hunt Steven C, Kubota Isao, Kawata Sumio, Kato Takeo
Abstract excerpt
Hepatic lipase (HL) plays a major role in the regulation of plasma lipids. Several groups seeking to find association between the gene encoding HL (LIPC) and plasma concentrations of high-density lipoprotein cholesterol (HDLc) using various methods and populations have reported conflicting results. We have approached the problem of demonstrating a relationship between the LIPC locus and HDLc by means of haplotype...
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