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Article

Mid-anaphase arrest in S. cerevisiae cells eliminated for the function of Cin8 and dynein.

Cellular and molecular life sciences : CMLS - 1 Jan 2009

Gerson-Gurwitz A, Movshovich N, Avunie R, Fridman V, Moyal K, Katz B, Hoyt M A, Gheber L

Abstract excerpt

S. cerevisiae anaphase spindle elongation is accomplished by the overlapping function of dynein and the kinesin-5 motor proteins, Cin8 and Kip1. Cin8 and dynein are synthetically lethal, yet the arrest phenotypes of cells eliminated for their function had not been identified. We found that at a non-permissive temperature, dyn1 Delta cells that carry a temperature-sensitive cin8 - 3 mutation arrest at mid-anaphase...

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Identifiers

PMID: 19099194
DOI: 10.1007/s00018-008-8479-2
PMCID: PMC11131513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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