Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Promoter methylation of HIN-1 in the progression to esophageal squamous cancer.

Epigenetics - 1 Nov 2008

Guo Mingzhou, Ren Jingli, Brock Malcolm V, Herman James G, Carraway Hetty E

Abstract excerpt

HIN-1 (High in normal-1) is a tumor suppressor gene that is highly expressed in many epithelial tissues, including breast lung, trachea, pancreas, prostrate and salivary gland. Inactivation of HIN-1 expression by promoter methylation is frequent in many epithelial carcinomas and carcinoma-in-situ...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokines
Share to Disease Progression
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

Share to Gene Expression Regulation, Neoplastic

Share to Gene Silencing

Share to Neoplasms, Squamous Cell

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 19098448
DOI: 10.4161/epi.3.6.7158

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19098448-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Promoter methylation of HIN-1 in the progression to esophageal squamous cancer.PMID 19098448Read ↗

Aberrant promoter methylation of HIN-1 gene may contribute to the pathogenesis of breast cancer: a meta-analysis.Semantic proximity Read ↗

Aberrant DNA Methylation in Esophageal Squamous Cell Carcinoma: Biological and Clinical ImplicationsSemantic proximity Read ↗

DNA hypermethyation and silencing ofPITX1correlated with advanced stage and poor postoperative prognosis of esophageal squamous cell carcinomaSemantic proximity Read ↗

Epigenetic biomarkers in esophageal cancer.Semantic proximity Read ↗

The detective, prognostic, and predictive value of DNA methylation in human esophageal squamous cell carcinomaSemantic proximity Read ↗

Characterization of epigenetic alterations in esophageal cancer by whole-genome bisulfite sequencingSemantic proximity Read ↗

Detection of LINE-1 hypomethylation in cfDNA of Esophageal Adenocarcinoma PatientsSemantic proximity Read ↗

Promoter Methylation in Cytology Specimens as an Early Detection Marker for Esophageal Squamous Dysplasia and Early Esophageal Squamous Cell CarcinomaSemantic proximity Read ↗

Accumulation of Promoter Methylation Suggests Epigenetic Progression in Squamous Cell Carcinoma of the EsophagusSemantic proximity Read ↗

Hypomethylation of Alu repetitive elements in esophageal mucosa, and its potential contribution to the epigenetic field for cancerization.Semantic proximity Read ↗

Molecular Characteristics of Basaloid Squamous Cell Carcinoma of the Esophagus: Analysis of KRAS, BRAF, and PIK3CA Mutations and LINE-1 Methylation.Semantic proximity Read ↗

Lack of HIN-1 methylation in BRCA1-linked and "BRCA1-like" breast tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.