Article

Characterization of epigenetic alterations in esophageal cancer by whole-genome bisulfite sequencing

2021-12-07

Abstract excerpt

Esophageal carcinoma is a common and aggressive malignancy, and its patients have dismal clinical outcomes. The epigenetic dysregulation in both major subtypes, esophageal squamous cell carcinoma (ESCC) and adenocarcinoma (EAC), awaits further characterization. Here, we perform whole-genome bisulfite sequencing (WGBS) on a total of 43 esophageal cancer and normal samples, generating one of the largest WGBS dataset...

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Literature Corpus work: 2e92a9c8-010c-5c40-88bb-6347d475b841
DOI: 10.1101/2021.12.05.471340

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